Description
Associate Scientific Researcher Caltech Job Category: Fulltime Regular Exempt Overtime Eligible: Exempt Benefits Eligible: Benefit Based Caltech is a world-renowned science and engineering institute that marshals some of the world’s brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary Caltech’s Division of Biology and Biological Engineering seeks a highly motivated Associate Scientific Researcher to work in the Glover Lab. The Associate Scientific Researcher should have expertise in studies of the Rac GTPase activating protein Arh15gap whose depletion can counter the effects of elevated Plk4 upon centriole re-duplication and its block to cell proliferation. The successful candidate will also determine effects of centriole elongation and cohesion upon centriole numbers and the ability of cells to proliferate. Essential Job Duties Organizes, plans, and conducts experiments to study and investigate scientific objectives of the research project. Tests whether the depletion of protein complexes regulating centriole length destabilizes the centriole duplication machinery and the extent to which loss of centriole cohesion is permissive for cell proliferation. Tests the extent and how Plk4’s function and cell proliferation depend upon Arh15gap per se; Rac; the Rac dependent kinases Pak1/2; and the downstream actin regulators Arp2/3. Analyzes and interprets data to determine if additional enhancements are required to improve the efficiency of the experiment. Provides guidance to research technicians and graduate students regarding formulation of hypothesis, planning of experiments, and interpretation of research results. Conducts literature research, co-authors results, and/or presents findings at meetings, scientific organizations, or conferences. Partners with PI and other research groups across disciplines and/or organizations in developing and testing highly sophisticated data acquisition, engineering techniques and systems, and contributes to the development and design of experimental techniques. Independently troubleshoots and provides solutions to a range of problems. Maintains detailed laboratory records. Other duties will be carried out as assigned. These include, but are not limited to, studies of the interface between the centrosome duplication cycle and ciliogenesis; studies of the roles of the Hippo and Wnt signaling pathways in regulating centrosome number; and studies of the roles of protein degradation pathways in eliminating supernumerary centrosomes. Basic Qualifications PhD in Molecular Biology, Cell Biology, or Biomedical Sciences. 10 years of post-doctoral research experience. Expertise in studies of the Rac GTPase activating protein Arh15gap. Excellent communication skills and the ability to interact professionally with students and all levels of staff, as well as with external collaborators. Ability to contribute to writing papers and grants. Ability to handle a variety of tasks simultaneously. Ability to resolve technical problems and adapt easily to changing needs and priorities. Must possess a high level of initiative. Required Documents Resume To be considered for this position please visit our web site and apply on line at the following link: https://hr.caltech.edu/work/job_openings We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. Copyright 2025 Jobelephant.com Inc. All rights reserved. Posted by the FREE value-added recruitment advertising agency jeid-b0012e3c2f34cd428d4e2449cc44e409